CKR-5 Polyclonal Antibody, 20ul[BT-AP14980] Pathway and Network Analysis The encoded protein contains a

The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD)

This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals

The encoded protein may bind single-stranded DNA

MIM 604833)

Two alternatively spliced transcript variants encoding the same protein

CKR-5 Polyclonal Antibody, 20ul[BT-AP14980] Pathway and Network Analysis The encoded protein contains aThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include