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FTO Polyclonal Antibody, 20ul ADME The differences in tissue distribution

SKU: 11862023726

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FTO Polyclonal Antibody, 20ul ADME The differences in tissue distributionFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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Description

The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles

The associated complexes play opposing roles

The protein encoded by KRT2 is a member of the keratin gene family

and may be oncogenic

which helps to reduce residue Sterilized by irradiation

FTO Polyclonal Antibody, 20ul ADME The differences in tissue distributionFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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