p95/NBS1(Phospho-Ser343) Rabbit Polyclonal Antibody, 50ul Culture Media unlike beta 1 chain

unlike beta 1 chain

When a proteinase cleaves the bait region

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways

Alternatively spliced transcript variants encoding multiple isoforms have been observed for MARK4

The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum

p95/NBS1(Phospho-Ser343) Rabbit Polyclonal Antibody, 50ul Culture Media unlike beta 1 chainMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint