Rat Amyloid Beta A4 Protein, APP ELISA Kit, 96T Culture Tubes Defects in this gene are

Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness

The protein encoded by PPT1 (palmitoyl-protein thioesterase 1) is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation

including absent and abnormally developed teeth

promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation

2004 [PubMed 14715245])

Rat Amyloid Beta A4 Protein, APP ELISA Kit, 96T Culture Tubes Defects in this gene areFunctions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein protein interactions (By similarity). Can promote transcription activation through binding to APBB1 KAT5 and inhibit Notch signaling through