IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis This receptor is reported to

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B

Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates| and may lead to Zellweger syndrome| severe mental retardation| and death in children

This gene encodes a member of the melanoma-inhibiting activity gene family

IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis This receptor is reported toIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.